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Supporting Innovative Research


The Alliance’s mission is to end colorectal cancer in our lifetime. By supporting innovative colorectal cancer research by top doctors and scientists, we take important steps toward realizing our vision — a world free of this disease.

Click on a type of research below to see who is using our funding to accelerate treatment, prevention, and a cure. 

Research Focus: Rectal Cancer

Dr. J. Joshua Smith, Memorial Sloan Kettering Cancer Center

Development of an Accurate Model for More Precise Treatment of the Rectal Cancer Patient

Study Description: Dr. J. Joshua Smith developed a model for the precise treatment of rectal cancer known as organoids, which better mimic patient-specific characteristics and serve as the optimal model for studying rectal cancer biology. These organoids are grown from very small amounts of tissue. This model has changed our ability to study rectal cancer and individual responses to treatment, providing patients with more precise therapies. Dr. Smith and team have published articles on their findings in three journals and, as a result of findings through the Alliance grant, have received a multi-million dollar grant from the National Cancer Institute.

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