Colorectal Cancer News
Compound Discovered in Florida Keys Shows Early Promise as Colon Cancer Treatment
A chemical compound made from a type of bacteria discovered in the Florida Keys has shown to be effective in preclinical experiments in battling colon cancer. The bacteria was discovered by a University of Florida pharmacy researcher.
The compound, called largazole because it was found in Key Largo, has been shown to hinder human cancer cell growth in cultures and rodents. Researchers are optimistic because while the chemical compound taken from the bacteria is a natural source, they have also been able to synthetically create the compound.
This compound is seemingly more promising than other natural products as an effective cancer-fighting drug because of three aspects. The availability of supply (it is abundant in nature), knowing the mode of action of the chemical compound, as well as the fact that the “cellular target is already a proven anticancer target known to result in the necessary selectivity for cancer cells over normal cells.”
Homewood, Linda. Compound Discovered in Florida Keys Shows Early Promise as Colon Cancer Treatment. University of Florida News. 2010 September 29.